9HMC

Crystal structure of PDE6D in complex with compound 5e

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	polymer	156	18269.9	2	UniProt (O43924)	Homo sapiens (human)	GMP-PDE delta,Protein p17
2	C, F (A, B)	4-[3,4-dimethyl-2-(4-methylphenyl)-7-oxidanylidene-pyrazolo[3,4-d]pyridazin-6-yl]-~{N}-heptyl-~{N}-(piperidin-4-ylmethyl)butane-1-sulfonamide	non-polymer		584.8	2	Chemie (A1IWC)
3	D, E (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	G (B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
5	H, I (A, B)	water	water		18.0	147	Chemie (HOH)

Sequence modifications

A, B: 1 - 150 (UniProt: O43924)

PDB	External Database	Details
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	36539.8
Non-Polymers*	Number of molecules	5
	Total formula weight	1459.9
All*	Total formula weight	37999.7

*Water molecules are not included.