9HMA

Cryo-EM structure of apo human separase

Summary for 9HMA

• Entry DOI: 10.2210/pdb9hma/pdb
• Related: 9HM7
• EMDB information: 52288 52290
• Descriptor: Separin, ZINC ION (2 entities in total)
• Functional Keywords: separase, cell cycle, scc1, rad21, protease, chromosome segregation, auto-cleavage
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 243216.53

Authors

Yu, J.,Schmidt, S.,Botto, M.,Boland, A. (deposition date: 2024-12-07, release date: 2025-09-03)

• Primary citation: Yu, J.,Schmidt, S.,Botto, M.,Ghent, C.M.,Morgan, D.O.,Boland, A.; Structural insights into cohesin cleavage by human separase; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.3 Å)