9HLH

Influenza Neuraminidase in complex with N-Acyl Oseltamivir inhibitor

This is a non-PDB format compatible entry.

Summary for 9HLH

• Entry DOI: 10.2210/pdb9hlh/pdb
• EMDB information: 52254
• Descriptor: Neuraminidase, (3~{S},4~{R},5~{R},6~{R})-4-acetamido-3-azanyl-5-pentan-3-yloxy-6-(pent-4-ynoylamino)cyclohexene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: influenza, neuraminidase, viral protein
• Biological source: Influenza A virus
• Total number of polymer chains: 4
• Total formula weight: 172561.04

Authors

Moran, E.,Davies, G. (deposition date: 2024-12-04, release date: 2025-12-17)

• Primary citation: Moran, E.,Vriends, M.,Calvelo, M.,Hansen, T.,Pickles, I.,Xin, X.,Biezeno, M.,Armstrong, Z.,Ferras, M.,Li, L.,Lilley, A.,Harvey, R.,Schroder, S.,Withers, S.,Van der Marel, G.,Artola, M.,Aerts, J.,Blaza, J.,Rovira, C.,Codee, J.,Davies, G.,Overkleeft, H.; Oseltamivir aziridines are neuraminidase imaging agents and potent anti-influenza agents; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.25 Å)