9HLH
Influenza Neuraminidase in complex with N-Acyl Oseltamivir inhibitor
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Neuraminidase | polymer | 387 | 42499.5 | 4 | UniProt (E0V7D1) Pfam (PF00064) | Influenza A virus | |
| 2 | E, H, K, N (A, B, C, D) | (3~{S},4~{R},5~{R},6~{R})-4-acetamido-3-azanyl-5-pentan-3-yloxy-6-(pent-4-ynoylamino)cyclohexene-1-carboxylic acid | non-polymer | 379.5 | 4 | Chemie (A1IVW) | |||
| 3 | F, I, L, O (A, B, C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 4 | G, J, M, P (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 5 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 392 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 83 - 469 (UniProt: E0V7D1)
| PDB | External Database | Details |
|---|---|---|
| Pro 99 | Ile 99 | conflict |
| Leu 100 | Tyr 100 | conflict |
| Val 161 | Cys 161 | conflict |
| Ser 165 | Glu 165 | conflict |
| Ala 172 | Ser 172 | conflict |
| Ile 177 | Val 177 | conflict |
| Thr 196 | Ser 196 | conflict |
| Ile 205 | Val 205 | conflict |
| Met 408 | Gln 408 | conflict |
| Val 419 | Arg 419 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 169998.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2562.9 | |
| All* | Total formula weight | 172561.0 |
