9HI2

STRUCTURE OF HUMAN UDP-GALACTOSE 4-EPIMERASE IN COMPLEX WITH COVALENT COMPOUND WBC10

This is a non-PDB format compatible entry.

Summary for 9HI2

• Entry DOI: 10.2210/pdb9hi2/pdb
• Descriptor: UDP-glucose 4-epimerase, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3-[[(5-cyclobutyl-1,2-oxazol-3-yl)carbamoylamino]methyl]benzenesulfonyl fluoride, ... (4 entities in total)
• Functional Keywords: glycosylation, metabolism, nucleotide-sugar, isomerase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 39342.39

Authors

Mouilleron, S.,Schumann, B.,Browne, W.,Purkiss, A.,Weckwerth, T.,Ogrodowicz, R.,Prema, R.,Kunzelmann, S.,Roustan, C. (deposition date: 2024-11-22, release date: 2025-12-03)

• Primary citation: Browne, W.,Schumann, B.,Purkiss, A.,Weckwerth, T.,Ogrodowicz, R.,Prema, R.,Kunzelmann, S.,Roustan, C.,Mouilleron, S.; Identification of Novel Inhibitors of Human UDP-Galactose-4-Epimerase (GalE) by Fragment-Based Lead Discovery; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.37 Å)