9HBM

Crystal structure of human NUDT14 in complex with a potent inhibitor (MA-955-10)

This is a non-PDB format compatible entry.

Summary for 9HBM

• Entry DOI: 10.2210/pdb9hbm/pdb
• Related: 9GZV
• Descriptor: Uridine diphosphate glucose pyrophosphatase NUDT14, 1-(1-methylpiperidin-4-yl)-3-(4-propan-2-yloxyphenyl)pyrazolo[3,4-d]pyrimidin-4-amine, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: adp-sugar pyrophosphatase, dimer, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 49238.10

Authors

Balikci, E.,Feyerherm, C.,Apostolidou, M.,Adcock, C.,McGown, A.,Spencer, J.,Huber, K. (deposition date: 2024-11-07, release date: 2025-11-19)

• Primary citation: Balikci, E.,Feyerherm, C.,Apostolidou, M.,Adcock, C.,McGown, A.,Spencer, J.,Huber, K.; Crystal structure of human NUDT14 in complex with a potent inhibitor (MA-955-10); To Be Published,

Experimental method

X-RAY DIFFRACTION (1.83 Å)