9HBM
Crystal structure of human NUDT14 in complex with a potent inhibitor (MA-955-10)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Uridine diphosphate glucose pyrophosphatase NUDT14 | polymer | 223 | 24228.3 | 2 | UniProt (O95848) | Homo sapiens (human) | UDPG pyrophosphatase,UGPPase,Nucleoside diphosphate-linked moiety X motif 14,Nudix motif 14 |
| 2 | C, E (A, B) | 1-(1-methylpiperidin-4-yl)-3-(4-propan-2-yloxyphenyl)pyrazolo[3,4-d]pyrimidin-4-amine | non-polymer | 366.5 | 2 | Chemie (A1ITN) | |||
| 3 | D, F (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 156 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 222 (UniProt: O95848)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48456.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 781.5 | |
| All* | Total formula weight | 49238.1 |
