9H5X

Crystal structure of human V122I transthyretin in complex with (3,4-dihydroxy-5-nitrophenyl)-(3-fluoro-5-hydroxyphenyl)methanone compound

Summary for 9H5X

• Entry DOI: 10.2210/pdb9h5x/pdb
• Descriptor: Transthyretin, (3-fluoranyl-5-oxidanyl-phenyl)-[3-nitro-4,5-bis(oxidanyl)phenyl]methanone (3 entities in total)
• Functional Keywords: t4 binding protein, amyloid, natural mutation, inhibitor compound, protein transport
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 27652.59

Authors

Varejao, N.,Pinheiro, F.,Pallares, I.,Ventura, S.,Reverter, D. (deposition date: 2024-10-23, release date: 2025-11-05)

• Primary citation: Varejao, N.,Pinheiro, F.,Pallares, I.,Ventura, S.,Reverter, D.; Crystal structure of human V122I transthyretin in complex with (3,4-dihydroxy-5-nitrophenyl)-(3-fluoro-5-hydroxyphenyl)methanone compound; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)