9H5X
Crystal structure of human V122I transthyretin in complex with (3,4-dihydroxy-5-nitrophenyl)-(3-fluoro-5-hydroxyphenyl)methanone compound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transthyretin | polymer | 125 | 13533.1 | 2 | UniProt (P02766) Pfam (PF00576) | Homo sapiens (human) | ATTR,Prealbumin,TBPA |
| 2 | C, D (A, B) | (3-fluoranyl-5-oxidanyl-phenyl)-[3-nitro-4,5-bis(oxidanyl)phenyl]methanone | non-polymer | 293.2 | 2 | Chemie (AQI) PubChem (165430622) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 114 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 125 (UniProt: P02766)
| PDB | External Database | Details |
|---|---|---|
| Ile 122 | Val 142 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27066.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 586.4 | |
| All* | Total formula weight | 27652.6 |
