9H2I

Dihydrolipoyl Dehydrogenase (E3) in complex with the binding domain of Dihydrolipoamide Acetyltransferase (E2) from the E. coli pyruvate dehydrogenase complex

Summary for 9H2I

Entry DOI	10.2210/pdb9h2i/pdb
Descriptor	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total)
Functional Keywords	complex, pyruvate dehydrogenase, electrostatic binding, flavoprotein
Biological source	Escherichia coli More
Total number of polymer chains	3
Total formula weight	110029.62
Authors	Bothe, S.N.,Zajec Hudnik, T.,Glockshuber, R. (deposition date: 2024-10-11, release date: 2025-10-29)
Primary citation	Bothe, S.N.,Racunica, D.,Zajec Hudnik, T.,Zdanowicz, R.,Bothe, A.,Giese, C.,Glockshuber, R. A cooperative binding mechanism steers the recruitment of peripheral subunits in the E. coli pyruvate dehydrogenase complex To Be Published,
Experimental method	X-RAY DIFFRACTION (1.97 Å)

Structure validation