9GVN

DEPEMOKIMAB FAB IN COMPLEX WITH INTERLEUKIN 5

Summary for 9GVN

• Entry DOI: 10.2210/pdb9gvn/pdb
• Descriptor: Interleukin-5, Fab heavy chain, Fab light chain, ... (7 entities in total)
• Functional Keywords: il-5, antibody, complex, epitope, cytokine, glycoprotein, immunoglobulin fold, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 123609.01

Authors

Somers, D.O. (deposition date: 2024-09-25, release date: 2026-01-14)

• Primary citation: Orecchia, M.,Welbeck, K.,Dexter, J.,Hook, L.,Akinseye, C.,Kot, M.,Lewis, A.,Somers, D.,Bhinder, T.,Hamblin, P.,Elsey, S.,Wille, D.,Grant, S.; Generation and preclinical assessment of depemokimab, an enhanced IL-5 antagonist monoclonal antibody; Heliyon, 12:-, 2026; DOI: 10.1016/j.heliyon.2025.e44247

Experimental method

X-RAY DIFFRACTION (1.933 Å)