9GVN

DEPEMOKIMAB FAB IN COMPLEX WITH INTERLEUKIN 5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002639	biological_process	positive regulation of immunoglobulin production
A	0005125	molecular_function	cytokine activity
A	0005137	molecular_function	interleukin-5 receptor binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005886	cellular_component	plasma membrane
A	0005895	cellular_component	interleukin-5 receptor complex
A	0006954	biological_process	inflammatory response
A	0007259	biological_process	cell surface receptor signaling pathway via JAK-STAT
A	0008284	biological_process	positive regulation of cell population proliferation
A	0019221	biological_process	cytokine-mediated signaling pathway
A	0030890	biological_process	positive regulation of B cell proliferation
A	0038043	biological_process	interleukin-5-mediated signaling pathway
A	0045645	biological_process	positive regulation of eosinophil differentiation
A	0045944	biological_process	positive regulation of transcription by RNA polymerase II
A	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
A	0071803	biological_process	positive regulation of podosome assembly
B	0002639	biological_process	positive regulation of immunoglobulin production
B	0005125	molecular_function	cytokine activity
B	0005137	molecular_function	interleukin-5 receptor binding
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005886	cellular_component	plasma membrane
B	0005895	cellular_component	interleukin-5 receptor complex
B	0006954	biological_process	inflammatory response
B	0007259	biological_process	cell surface receptor signaling pathway via JAK-STAT
B	0008284	biological_process	positive regulation of cell population proliferation
B	0019221	biological_process	cytokine-mediated signaling pathway
B	0030890	biological_process	positive regulation of B cell proliferation
B	0038043	biological_process	interleukin-5-mediated signaling pathway
B	0045645	biological_process	positive regulation of eosinophil differentiation
B	0045944	biological_process	positive regulation of transcription by RNA polymerase II
B	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
B	0071803	biological_process	positive regulation of podosome assembly

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
D	TYR198-HIS204
C	TYR200-HIS206

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Site: {"description":"Not glycosylated","evidences":[{"source":"PubMed","id":"2361960","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"2361960","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Glycosylation: {"description":"O-linked (GalNAc...) threonine","evidences":[{"source":"PubMed","id":"2361960","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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