9GL8

EGFR Exon20 insertion mutant NPG bound with STX-721

This is a non-PDB format compatible entry.

Summary for 9GL8

• Entry DOI: 10.2210/pdb9gl8/pdb
• Descriptor: Epidermal growth factor receptor, SODIUM ION, GLYCEROL, ... (6 entities in total)
• Functional Keywords: kinase, inhibitor, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 39466.88

Authors

Hilbert, B.J.,Brooijmans, N.,Milgram, B.C.,Pagliarini, R.A. (deposition date: 2024-08-27, release date: 2025-05-14)

• Primary citation: Milgram, B.C.,Pagliarini, R.A.,Borrelli, D.R.,OHearn, E.,Huff, M.R.,Ladd, B.,Brooijmans, N.,Henderson, J.A.,Hilbert, B.J.,Wang, W.,Ito, T.,Jonsson, P.,Jackson, E.L.,Guzman-Perez, A.; EGFR Exon20 insertion mutant NPG bound with STX-721; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.632 Å)