Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Epidermal growth factor receptor | polymer | 338 | 38677.6 | 1 | UniProt (P00533) Pfam (PF07714) | Homo sapiens (human) | Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1 |
| 2 | B, C (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 3 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | F (A) | (2R,3S)-3-[(3-chloranyl-2-methoxy-phenyl)amino]-2-[3-[2-[(2R)-1-[(E)-4-(dimethylamino)but-2-enoyl]-2-methyl-pyrrolidin-2-yl]ethynyl]pyridin-4-yl]-1,2,3,5,6,7-hexahydropyrrolo[3,2-c]pyridin-4-one | non-polymer | 589.1 | 1 | Chemie (A1IMT) | |||
| 6 | G (A) | water | water | 18.0 | 374 | Chemie (HOH) |
Sequence modifications
A: 695 - 1022 (UniProt: P00533)
| PDB | External Database | Details |
|---|---|---|
| Met 694 | - | initiating methionine |
| Asn 770 | - | insertion |
| Pro 770 | - | insertion |
| Gly 770 | - | insertion |
| Arg 948 | Val 948 | engineered mutation |
| His 1023 | - | expression tag |
| His 1024 | - | expression tag |
| His 1025 | - | expression tag |
| His 1026 | - | expression tag |
| His 1027 | - | expression tag |
| His 1028 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38677.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 789.3 | |
| All* | Total formula weight | 39466.9 |
