9GC7

Mineralocorticoid receptor in complex with acylurea antagonists.

This is a non-PDB format compatible entry.

Summary for 9GC7

• Entry DOI: 10.2210/pdb9gc7/pdb
• Descriptor: Mineralocorticoid receptor, Nuclear receptor coactivator 1, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (6 entities in total)
• Functional Keywords: mineralocorticoid r, nuclear hormone receptor, steroid receptor, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 36858.14

Authors

Edman, K.,Aagaard, A.,Barlind, L. (deposition date: 2024-08-01, release date: 2026-02-18)

• Primary citation: Aaagaard, A.,Bamberg, K.,Barlind, L.,Edman, K.,Fredenwall, M.,Granberg, K.L.,Hansson, E.,Hogner, A.,Ivarsson, I.,Johansson, M.,Johansson, U.,Karlsson, U.,Lindberg, J.,Lindmarg, B.,Liu, D.,Nordqvist, A.,O'Mahony, G.,Sorensen, H.,William-Olsson, L.,Yuan, Z.Q.; Mineralocorticoid receptor antagonists with an acylurea as a key polar interaction motif; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.46 Å)