Summary for 9FYD
Entry DOI | 10.2210/pdb9fyd/pdb |
Descriptor | Tubulin alpha-1B chain, cryptophycin-uD[Dab], PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (12 entities in total) |
Functional Keywords | cell cycle, cytoskeleton, microtubule, tubulin, cryptophycin, microtubule targting agent |
Biological source | Rattus norvegicus (Norway rat) More |
Total number of polymer chains | 6 |
Total formula weight | 265856.73 |
Authors | Dessin, C.,Schachtsiek, T.,Voss, J.,Abel, A.-C.,Neumann, B.,Stammler, H.-G.,Prota, A.E.,Sewald, N. (deposition date: 2024-07-03, release date: 2024-10-09) |
Primary citation | Dessin, C.,Schachtsiek, T.,Voss, J.,Abel, A.C.,Neumann, B.,Stammler, H.G.,Prota, A.E.,Sewald, N. Highly Cytotoxic Cryptophycin Derivatives with Modification in Unit D for Conjugation. Angew.Chem.Int.Ed.Engl., :e202416210-e202416210, 2024 Cited by PubMed: 39324938DOI: 10.1002/anie.202416210 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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