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9FPX

Crystal structure of DYRK1A in complex with Curcumin

Summary for 9FPX
Entry DOI10.2210/pdb9fpx/pdb
DescriptorDual specificity tyrosine-phosphorylation-regulated kinase 1A, curcumin, TETRAETHYLENE GLYCOL, ... (4 entities in total)
Functional Keywordskinase, kinase inhibitor, dyrk1a, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight87554.53
Authors
Grygier, P.,Pustelny, K.,Czarna, A. (deposition date: 2024-06-14, release date: 2025-06-25)
Primary citationMenezes, F.,Grygier, P.,Pustelny, K.,Popowicz, G.,Czarna, A.
Curcumin Inhibition of DYRK Kinases
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.69 Å)
Structure validation

246905

PDB entries from 2025-12-31

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