9FJH

Two PLK1 PBD proteins bound to CENP-U(58-114) phosphorylated at Thr78 and Thr98

Summary for 9FJH

• Entry DOI: 10.2210/pdb9fjh/pdb
• Descriptor: Serine/threonine-protein kinase PLK1, Centromere protein U, TRIETHYLENE GLYCOL, ... (6 entities in total)
• Functional Keywords: plk1, cell cycle, ccan, kinase, mitosis, kinetochore, cenp-u, phosphorylation
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 67175.55

Authors

Ren, L.,Gasper, R.,Vetter, I.R.,Musacchio, A. (deposition date: 2024-05-31, release date: 2025-09-24)

• Primary citation: Ren, L.,Gasper, R.,Vetter, I.R.,Musacchio, A.; Structural and molecular basis of kinaseregulated inner-kinetochore recruitment of PLK1 by CENP-U; To be published,

Experimental method

X-RAY DIFFRACTION (2.15 Å)