9FI9

Human PIF + Z48847594 (OCCUPANCY 0.7)

Summary for 9FI9

• Entry DOI: 10.2210/pdb9fi9/pdb
• Related: 6HPH
• Descriptor: ATP-dependent DNA helicase PIF1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: helicase, inhibitor, complex, amppnp, dna binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 46286.36

Authors

Bax, B.D.,Sanders, C.M.,Antson, A.A.,Brandao-Neto, J. (deposition date: 2024-05-28, release date: 2024-10-02)

• Primary citation: Wever, M.,Scommegna, F.,Egea Rodriguez, S.,Dehghani-Tafti, S.,Brandao-Neto, J.,Poisson, J.,Helfrich, I.,Antson, A.,Rodeschini, V.,Bax, B.,Roche, D.,Sanders, C.; Structure-based discovery of first inhibitors targeting the helicase activity of human PIF1; Nucleic Acids Research, 2024

Experimental method

X-RAY DIFFRACTION (1.727 Å)