9FH5

Cryo-EM Structure of Amyloid-beta Fibrils Carrying the Uppsala AbetaUpp(1-42)delta(19-24) Mutation - Polymorph 4

Summary for 9FH5

• Entry DOI: 10.2210/pdb9fh5/pdb
• EMDB information: 50440
• Descriptor: Amyloid-beta precursor protein (1 entity in total)
• Functional Keywords: amyloid fibril, protein fibril
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 20
• Total formula weight: 76226.60

Authors

Zielinski, M.,Peralta Reyes, F.S.,Gremer, L.,Pagnon de la Vega, M.,Roeder, C.,Heidler, T.V.,Syvaenen, S.,Willbold, D.,Sehlin, D.,Ingelsson, M.,Schroeder, G.F. (deposition date: 2024-05-26, release date: 2025-06-11)

• Primary citation: Zielinski, M.,Peralta Reyes, F.S.,Gremer, L.,Pagnon de la Vega, M.,Roeder, C.,Heidler, T.V.,Syvaenen, S.,Willbold, D.,Sehlin, D.,Ingelsson, M.,Schroeder, G.F.; Cryo-EM Structures of Amyloid-beta Fibrils from human and murine brains carrying the Uppsala AbetaUpp(1-42)delta(19-24) mutation; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.8 Å)