9FAS

CryoEM structure of human full-length alpha1beta3gamma2L GABA(A)R in complex with pregnenolone sulfate

Summary for 9FAS

• Entry DOI: 10.2210/pdb9fas/pdb
• EMDB information: 50280
• Descriptor: Gamma-aminobutyric acid receptor subunit alpha-1, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, DECANE, ... (18 entities in total)
• Functional Keywords: gaba, neurotransmission, ternary complex, inhibitory synapse, neurosteroid, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 259226.79

Authors

Kasaragod, V.B.,Aricescu, A.R. (deposition date: 2024-05-10, release date: 2025-05-28)

• Primary citation: Kasaragod, V.B.,Aricescu, A.R.; CryoEM structure of human full-length alpha1beta3gamma2L GABA(A)R in complex with pregnenolone sulfate; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.5 Å)