9FAK

CryoEM structure of human full-length alpha1beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2, GABA and Megabody38 in a desensitised state (StateD2)

Summary for 9FAK

• Entry DOI: 10.2210/pdb9fak/pdb
• EMDB information: 50274
• Descriptor: Gamma-aminobutyric acid receptor subunit alpha-1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (23 entities in total)
• Functional Keywords: gaba, neurotransmission, ternary complex, inhibitory postsynapse, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 9
• Total formula weight: 404286.14

Authors

Kasaragod, V.B.,Aricescu, A.R. (deposition date: 2024-05-10, release date: 2025-07-02)

• Primary citation: Kasaragod, V.B.,Aricescu, A.R.; CryoEM structure of human full-length alpha1beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2, GABA and Megabody38 in a desensitised state (StateD2); To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.6 Å)