Summary for 9F9L
Entry DOI | 10.2210/pdb9f9l/pdb |
Related | 9F98 9F99 9F9A 9F9K |
Descriptor | Crossover junction endonuclease MUS81, Crossover junction endonuclease EME1, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | endonuclease, fragment, drug discovery, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 141446.11 |
Authors | Collie, G.W. (deposition date: 2024-05-07, release date: 2024-07-03, Last modification date: 2024-07-31) |
Primary citation | Collie, G.W.,Borjesson, U.,Chen, Y.,Dong, Z.,Di Fruscia, P.,Gohlke, A.,Hoyle, A.,Hunt, T.A.,Jesani, M.H.,Luo, H.,Luptak, J.,Milbradt, A.G.,Narasimhan, P.,Packer, M.,Patel, S.,Qiao, J.,Storer, R.I.,Stubbs, C.J.,Tart, J.,Truman, C.,Wang, A.T.,Wheeler, M.G.,Winter-Holt, J. Fragment-Based Discovery of Novel MUS81 Inhibitors. Acs Med.Chem.Lett., 15:1151-1158, 2024 Cited by PubMed: 39015284DOI: 10.1021/acsmedchemlett.3c00453 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
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