9F45
cryo-EM structure of human LST2 bound to human mTOR complex 1
Summary for 9F45
| Entry DOI | 10.2210/pdb9f45/pdb |
| EMDB information | 50184 |
| Descriptor | Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8, Regulatory-associated protein of mTOR, ... (5 entities in total) |
| Functional Keywords | mtor, mtorc1, lst2, zfyve28, egfr, tos, signaling protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 8 |
| Total formula weight | 1150394.45 |
| Authors | |
| Primary citation | Battaglioni, S.,Craigie, L.M.,Filippini, S.,Maier, T.,Hall, M.N. mTORC1 phosphorylates and stabilizes LST2 to negatively regulate EGFR Proc.Natl.Acad.Sci.USA, 2024 |
| Experimental method |
Structure validation
No wwPDB Validation report is currently available for this entry.
