9EO4
Outward-open structure of human dopamine transporter bound to cocaine
Summary for 9EO4
| Entry DOI | 10.2210/pdb9eo4/pdb |
| EMDB information | 19845 |
| Descriptor | Sodium-dependent dopamine transporter, CHOLESTEROL, CHOLESTEROL HEMISUCCINATE, ... (7 entities in total) |
| Functional Keywords | neurotransmitter/sodium symporters, monoamine transporter, dopamine transporter, slc6, membrane protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 74217.76 |
| Authors | Nielsen, J.C.,Salomon, K.,Kalenderoglou, I.E.,Bargmeyer, S.,Pape, T.,Shahsavar, A.,Loland, C.J. (deposition date: 2024-03-14, release date: 2024-07-03, Last modification date: 2024-08-21) |
| Primary citation | Nielsen, J.C.,Salomon, K.,Kalenderoglou, I.E.,Bargmeyer, S.,Pape, T.,Shahsavar, A.,Loland, C.J. Structure of the human dopamine transporter in complex with cocaine. Nature, 2024 Cited by PubMed: 39112703DOI: 10.1038/s41586-024-07804-3 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.66 Å) |
Structure validation
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