9EIC

Crystal structure of unbound N-SH2 domain of SHP2 with T42A mutation

Summary for 9EIC

• Entry DOI: 10.2210/pdb9eic/pdb
• Related: 9EH9 9EHA 9EHD
• Descriptor: Isoform 1 of Tyrosine-protein phosphatase non-receptor type 11, PHOSPHATE ION (3 entities in total)
• Functional Keywords: shp2, phosphatase, sh2, allostery, phosphotyrosine, activation, protein binding
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 12462.54

Authors

Padua, R.A.P.,Glaser, A.,Ojoawo, A.,Kern, D. (deposition date: 2024-11-25, release date: 2026-01-07)

• Primary citation: Padua, R.A.P.,Glaser, A.,Ojoawo, A.,Kern, D.; Crystal structure of unbound N-SH2 domain of SHP2 with T42A mutation; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.58 Å)