9EBM

Piperazate synthase (PipS) in complex with haem and N5-OH-L-ornithine

Summary for 9EBM

• Entry DOI: 10.2210/pdb9ebm/pdb
• Related: 9EBK
• Descriptor: Piperazate synthase, PROTOPORPHYRIN IX CONTAINING FE, N~5~-hydroxy-L-ornithine, ... (5 entities in total)
• Functional Keywords: n-n bond, natural product biosynthesis, heme, piperazate, piperazic acid, biosynthetic protein
• Biological source: Streptomyces griseus subsp. griseus
• Total number of polymer chains: 2
• Total formula weight: 52017.77

Authors

Higgins, M.A.,Ryan, K.S. (deposition date: 2024-11-12, release date: 2025-01-22, Last modification date: 2025-02-26)

• Primary citation: Higgins, M.A.,Shi, X.,Soler, J.,Harland, J.B.,Parkkila, T.,Lehnert, N.,Garcia-Borras, M.,Du, Y.L.,Ryan, K.S.; Structure and mechanism of haem-dependent nitrogen-nitrogen bond formation in piperazate synthase; Nat Catal, 2025; DOI: 10.1038/s41929-024-01280-8

Experimental method

X-RAY DIFFRACTION (1.92 Å)