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9E9S

Cryo-EM structure of the PGD2-bound prostaglandin D2 receptor (DP1)-Gs complex

Summary for 9E9S
Entry DOI10.2210/pdb9e9s/pdb
EMDB information47802
DescriptorGuanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (9 entities in total)
Functional Keywordsgpcr, dp1, bw245c, prostaglandin d2 receptor, prostanoid dp receptor, pgd receptor, ptgdr, gs protein, dp1-selective agonist, pgd2, membrane protein
Biological sourceHomo sapiens (human)
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Total number of polymer chains5
Total formula weight150899.05
Authors
Davoudinasab, B.,Cherezov, V.,Han, G.W.,KIm, D. (deposition date: 2024-11-08, release date: 2025-09-03)
Primary citationDavoudinasab, B.,Han, G.W.,Cherezov, V.
Cryo-EM structure of inactive and active prostaglandin D2 receptor
To Be Published,
Experimental method
ELECTRON MICROSCOPY (2.68 Å)
Structure validation

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