9E51

Cryo-EM structure of human LPHN2 (ADGRL2)/G13 complex in lipid nanodiscs

Summary for 9E51

• Entry DOI: 10.2210/pdb9e51/pdb
• EMDB information: 47522
• Descriptor: Isoform 2 of Guanine nucleotide-binding protein subunit alpha-13, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• Functional Keywords: adhesion gpcr, tethered agonist, latrophilin-2, lphn2 (adgrl2), heterotrimeric g protein, cryo-em, lipid nanodiscs, membrane protein, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 109517.22

Authors

He, F.,Skiniotis, G. (deposition date: 2024-10-26, release date: 2025-11-12)

• Primary citation: He, F.,Skiniotis, G.; Cryo-EM structure of G13-bound human LPHN2 (ADGRL2) in lipid nanodiscs; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.9 Å)