9E4V

The structure of human vacuolar protein sorting 34 catalytic domain bound to MES

Summary for 9E4V

• Entry DOI: 10.2210/pdb9e4v/pdb
• Related: 9DKP
• Descriptor: Phosphatidylinositol 3-kinase catalytic subunit type 3, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, TETRAETHYLENE GLYCOL, ... (9 entities in total)
• Functional Keywords: phosphatidylinositol 3-phosphate, lipid regulator, autophagy, membrane trafficking, endocytosis, enzyme, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 69393.14

Authors

Abiodun, W.O.,Fullmer, A.,Tsubaki, E.,Doukov, T.,Moody, J.D. (deposition date: 2024-10-25, release date: 2024-11-06)

• Primary citation: Abiodun, W.O.,Dass, R.,Fullmer, A.,Singleton, J.D.,Tsubaki, E.,Cartwright, J.,Litchfield, C.,Doukov, T.,Peterson, M.A.,Moody, J.D.; Facile Bacterial Production of Human Vacuolar Protein Sorting 34 Enables Structural Characterization of Novel Inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.36 Å)