9E4V
The structure of human vacuolar protein sorting 34 catalytic domain bound to MES
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Phosphatidylinositol 3-kinase catalytic subunit type 3 | polymer | 594 | 68149.9 | 1 | UniProt (Q8NEB9) Pfam (PF00613) Pfam (PF00454) | Homo sapiens (human) | PI3-kinase type 3,PI3K type 3,PtdIns-3-kinase type 3,Phosphatidylinositol 3-kinase p100 subunit,Phosphoinositide-3-kinase class 3,hVps34 |
| 2 | B (B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 3 | C (B) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 4 | D (B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 5 | E, F, L, M (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 4 | Chemie (PEG) | |||
| 6 | G (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | H, I, J, K (B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 8 | N, O, P (B) | POTASSIUM ION | non-polymer | 39.1 | 3 | Chemie (K) | |||
| 9 | Q (B) | water | water | 18.0 | 91 | Chemie (HOH) |
Sequence modifications
B: 290 - 871 (UniProt: Q8NEB9)
| PDB | External Database | Details |
|---|---|---|
| Met 278 | - | expression tag |
| Gly 279 | - | expression tag |
| His 280 | - | expression tag |
| His 281 | - | expression tag |
| His 282 | - | expression tag |
| His 283 | - | expression tag |
| His 284 | - | expression tag |
| His 285 | - | expression tag |
| His 286 | - | expression tag |
| His 287 | - | expression tag |
| His 288 | - | expression tag |
| His 289 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 68149.9 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1243.3 | |
| All* | Total formula weight | 69393.1 |
