9E3U

Cryo-EM structure of DNMT 3A2/3B3 tetramer bound to a di-nucleosome with a 25 base-pair linker

Summary for 9E3U

Entry DOI	10.2210/pdb9e3u/pdb
Related	9E00 9E05
EMDB information	47496
Descriptor	Histone H3.2, S-ADENOSYL-L-HOMOCYSTEINE, Histone H4, ... (10 entities in total)
Functional Keywords	dna methylation, dnmt 3a2/3b3, di-nucleosome, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
Biological source	Homo sapiens (human) More
Total number of polymer chains	15
Total formula weight	627838.96
Authors	Xie, X.,Zhou, X.E.,Worden, E.,Jones, P. (deposition date: 2024-10-24, release date: 2026-01-21)
Primary citation	Xie, X.,Liu, M.,Zhou, X.E.,Worden, E.,Jones, P. The structural basis for de novo DNA methylation in chromatin To Be Published,
Experimental method	ELECTRON MICROSCOPY (4.9 Å)

Structure validation