9E2D

Cryo-EM structure of human DNMT3A2-DNMT3B3 complex bound to a di-nucleosome with a five base pair linker

Summary for 9E2D

• Entry DOI: 10.2210/pdb9e2d/pdb
• Related: 9E00 9E05
• EMDB information: 47448
• Descriptor: Histone H3.2, S-ADENOSYL-L-HOMOCYSTEINE, Histone H4, ... (10 entities in total)
• Functional Keywords: dnmt3a, dnmt3b, nucleosome, dna methylation, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 26
• Total formula weight: 1074017.61

Authors

Xie, X.,Liu, M.,Zhou, X.E.,Worden, E.,Jones, P. (deposition date: 2024-10-22, release date: 2026-02-18)

• Primary citation: Xie, X.,Liu, M.,Zhou, X.E.,Worden, E.,Jones, P.; The structural basis for de novo DNA methylation in chromatin; To Be Published,

Experimental method

ELECTRON MICROSCOPY (6.08 Å)