9E0R

Cryo-EM structure of a single nucleosome (1) focus of human DNMT3A2-DNMT3B3 complex bound to di-nucleosome

Summary for 9E0R

Entry DOI	10.2210/pdb9e0r/pdb
Related	9E00 9E05
EMDB information	47367
Descriptor	Histone H3.2, Histone H4, Histone H2A, ... (7 entities in total)
Functional Keywords	dnmt3a2, dnmt3b3, dna methylation, di-nucleosome, dna binding protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	12
Total formula weight	206829.91
Authors	Xie, X.,Zhou, X.E.,Worden, E.J.,Jones, P.A. (deposition date: 2024-10-18, release date: 2026-02-18)
Primary citation	Xie, X.,Liu, M.,Zhou, X.E.,Worden, E.J.,Jones, P.A. The structure basis for de novo DNA methylation in chromatin To Be Published,
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation