9E0R
Cryo-EM structure of a single nucleosome (1) focus of human DNMT3A2-DNMT3B3 complex bound to di-nucleosome
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Histone H3.2 | polymer | 135 | 15303.9 | 2 | UniProt (Q71DI3) Pfam (PF00125) | Homo sapiens (human) | H3-clustered histone 13,H3-clustered histone 14,H3-clustered histone 15,Histone H3/m,Histone H3/o |
| 2 | B, F (B, F) | Histone H4 | polymer | 103 | 11394.4 | 2 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (human) | |
| 3 | C, G (C, G) | Histone H2A | polymer | 129 | 13978.2 | 2 | Pfam (PF00125) Pfam (PF16211) UniProt (by SIFTS) (P0C0S8) | Homo sapiens | |
| 4 | D, H (D, H) | Histone H2B | polymer | 123 | 13655.9 | 2 | Pfam (PF00125) UniProt (by SIFTS) (P06899) | Homo sapiens | |
| 5 | I (I) | DNA (155-MER) | polymer | 155 | 48012.6 | 1 | Homo sapiens | ||
| 6 | J (J) | DNA (155-MER) | polymer | 155 | 47683.4 | 1 | Homo sapiens | ||
| 7 | K, L (L, K) | DNA (cytosine-5)-methyltransferase 3B | polymer | 11 | 1234.5 | 2 | UniProt (Q9UBC3) | Homo sapiens (human) | Dnmt3b,DNA methyltransferase HsaIIIB,DNA MTase HsaIIIB,M.HsaIIIB |
Sequence modifications
A, E: 1 - 135 (UniProt: Q71DI3)
L, K: 736 - 746 (UniProt: Q9UBC3)
| PDB | External Database | Details |
|---|---|---|
| Ala 102 | Gly 103 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 739 | Gly 822 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 206829.9 | |
| All* | Total formula weight | 206829.9 |
