9E0F

A focus of DNMT tetramer (1) of the cryo-EM structure of human DNMT3A2-DNMT3B3 complex bound to di-nucleosome

Summary for 9E0F

• Entry DOI: 10.2210/pdb9e0f/pdb
• Related: 9E00 9E05
• EMDB information: 47354
• Descriptor: Isoform 3 of DNA (cytosine-5)-methyltransferase 3B, DNA (cytosine-5)-methyltransferase 3A, ZINC ION, ... (4 entities in total)
• Functional Keywords: dnmt3a2, dnmt3b3, dna methylation, di-nucleosome, dna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 330591.69

Authors

Xie, X.,Zhou, X.E.,Worden, E.J.,Jones, P.A. (deposition date: 2024-10-17, release date: 2026-02-18)

• Primary citation: Xie, X.,Liu, M.,Zhou, X.E.,Worden, E.J.,Jones, P.A.; The structure basis for de novo DNA methylation in chromatin; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.46 Å)