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9E09

Cryo-EM structure a single nucleosome (2) focus of human DNMT3A2-DNMT3B3 complex bound to di-nucleosome

Summary for 9E09
Entry DOI10.2210/pdb9e09/pdb
EMDB information47353
DescriptorHistone H3.2, Histone H4, Histone H2A, ... (8 entities in total)
Functional Keywordsdnmt3a2, dnmt3b3, dna methylation, di-nucleosome, dna binding protein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains12
Total formula weight207561.45
Authors
Xie, X.,Zhou, X.E.,Worden, E.J.,Jones, P.A. (deposition date: 2024-10-17, release date: 2026-02-18)
Primary citationXie, X.,Liu, M.,Zhou, X.E.,Worden, E.J.,Jones, P.A.
The structure basis for de novo DNA methylation in chromatin
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.72 Å)
Structure validation

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PDB entries from 2026-06-03

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