9DZ4

Cryo-EM Structure of Receptor Tyrosine Kinase ROS1 in Complex with Fab-CT4

Summary for 9DZ4

• Entry DOI: 10.2210/pdb9dz4/pdb
• EMDB information: 47324
• Descriptor: Proto-oncogene tyrosine-protein kinase ROS, Fab-CT4 light chain, Fab-CT4 heavy chain, ... (5 entities in total)
• Functional Keywords: receptor tyrosine kinase, ros1 extracellular bent-over conformation, inhibitory fab-ct4, transferase-immune system complex, transferase/immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 3
• Total formula weight: 165478.05

Authors

Li, H.,Klein, D. (deposition date: 2024-10-15, release date: 2026-02-25)

• Primary citation: Li, H.,Klein, D.; Structural basis for regulation of the receptor tyrosine kinase ROS1; To Be Published, ; DOI: 10.1038/s41467-026-69630-7

Experimental method

ELECTRON MICROSCOPY (2.99 Å)