9DZ4
Cryo-EM Structure of Receptor Tyrosine Kinase ROS1 in Complex with Fab-CT4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proto-oncogene tyrosine-protein kinase ROS | polymer | 1011 | 113126.4 | 1 | UniProt (Q78DX7) | Mus musculus (house mouse) | Proto-oncogene c-Ros,Proto-oncogene c-Ros-1,Receptor tyrosine kinase c-ros oncogene 1,c-Ros receptor tyrosine kinase |
| 2 | B (B) | Fab-CT4 light chain | polymer | 228 | 24795.4 | 1 | Homo sapiens (human) | ||
| 3 | C (C) | Fab-CT4 heavy chain | polymer | 238 | 25583.4 | 1 | Homo sapiens (human) | ||
| 4 | D (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E, F, G, H, I... (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) |
Sequence modifications
A: 27 - 1034 (UniProt: Q78DX7)
| PDB | External Database | Details |
|---|---|---|
| Ser 24 | - | expression tag |
| Leu 25 | - | expression tag |
| Asp 26 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 163505.2 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1548.5 | |
| All* | Total formula weight | 165478.0 |
