9DWY

Cryo-EM structure of human MCT8 in complex with thyroid hormone T3

Summary for 9DWY

• Entry DOI: 10.2210/pdb9dwy/pdb
• EMDB information: 47274
• Descriptor: Monocarboxylate transporter 8, 3,5,3'TRIIODOTHYRONINE (2 entities in total)
• Functional Keywords: slc transporter, thyroid hormone, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 63980.20

Authors

Ge, Y.,Dou, T.,Jiang, J.,Huang, P. (deposition date: 2024-10-10, release date: 2025-07-16)

• Primary citation: Ge, Y.,Dou, T.,Nguyen, T.U.,Yadav, G.P.,Wensel, T.G.,Jiang, J.,Huang, P.; Structural insights into brain thyroid hormone transport via MCT8 and OATP1C1; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.9 Å)