9DP1

APE1 N174A Substrate Complex with Abasic DNA

Summary for 9DP1

• Entry DOI: 10.2210/pdb9dp1/pdb
• Descriptor: DNA repair nuclease/redox regulator APEX1, mitochondrial, DNA (5'-D(P*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*(3DR)P*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... (4 entities in total)
• Functional Keywords: ape1, apex1, endonuclease, dna repair, hydrolase-dna complex, hydrolase/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 75008.12

Authors

DeHart, K.M.,Freudenthal, B.D. (deposition date: 2024-09-20, release date: 2024-10-09)

• Primary citation: DeHart, K.D.,Hoitsma, N.M.,Thompson, S.H.,Freudenthal, B.D.; N174 Physically and Chemically Stabilizes the Endonuclease Reaction of APE1; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.29 Å)