9DFW

X-ray crystal structure of an engineered Viperin-like enzyme from T. virens with bound CTP and SAM

Summary for 9DFW

• Entry DOI: 10.2210/pdb9dfw/pdb
• Related: 9DFN 9DFU
• Descriptor: Radical SAM core domain-containing protein, IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE, ... (8 entities in total)
• Functional Keywords: engineered viperin-like enzyme, viperin-like enzyme, ctp, sam, 4fe-4s cluster, ddhctp, antiviral protein
• Biological source: Trichoderma virens
• Total number of polymer chains: 3
• Total formula weight: 113448.66

Authors

Lachowicz, J.C.,Bonanno, J.B.,Grove, T.L. (deposition date: 2024-08-30, release date: 2025-02-12)

• Primary citation: Lachowicz, J.C.,Grudman, S.,Bonanno, J.B.,Fiser, A.,Grove, T.L.; Structural Insights from Active Site Variants and B-8 Loop Interactions in Viperin-like Enzymes; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.677 Å)