9CZE

High-Resolution Structure of Human DHODH for Molecular Replacement in Fragment Screening Campaign

Summary for 9CZE

• Entry DOI: 10.2210/pdb9cze/pdb
• Descriptor: Dihydroorotate dehydrogenase (quinone), mitochondrial, SULFATE ION, DIMETHYL SULFOXIDE, ... (8 entities in total)
• Functional Keywords: crystallographic fragment screening, fragment-free protein, ligand identification., oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 41204.15

Authors

Purificacao, A.D.,Benz, L.S.,Froes, T.Q.,Weiss, M.S.,Nonato, M.C. (deposition date: 2024-08-05, release date: 2025-10-29)

• Primary citation: Purificacao, A.D.,Benz, L.S.,Froes, T.Q.,Weiss, M.S.,Nonato, M.C.; Unexplored binding-sites on human DHODH identified by crystallographic fragment screening.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.6 Å)