9CY0

Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with AVI-4206

This is a non-PDB format compatible entry.

Summary for 9CY0

• Entry DOI: 10.2210/pdb9cy0/pdb
• Descriptor: Papain-like protease Non-structural protein 3, N-{4-[(2,2-dimethyl-5-oxopyrrolidin-1-yl)amino]-9H-pyrimido[4,5-b]indol-8-yl}-N'-ethylurea (3 entities in total)
• Functional Keywords: macrodomain, adp-ribose, sars-cov-2, viral protein, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 2
• Total formula weight: 37314.41

Authors

Correy, G.J.,Fraser, J.S. (deposition date: 2024-08-01, release date: 2025-11-12)

• Primary citation: Correy, G.J.,Fraser, J.S.; Ligand screen against SARS-CoV-2 NSP3 macrodomain; To Be Published,

Experimental method

X-RAY DIFFRACTION (0.8 Å)