9CB1

Cryo-EM Structure of the Human Neutralizing Antibody 5-1 in Complex with Prefusion Human Metapneumovirus F Glycoprotein

Summary for 9CB1

• Entry DOI: 10.2210/pdb9cb1/pdb
• EMDB information: 45412
• Descriptor: 5-1 Fab Heavy Chain Variable Domain, 5-1 Fab Light Chain Variable Domain, Fusion glycoprotein F0, ... (4 entities in total)
• Functional Keywords: hmpv f, 5-1 antibody, antibody, viral protein-immune system, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 9
• Total formula weight: 323014.23

Authors

Guo, L.Q.,McLellan, J.S. (deposition date: 2024-06-18, release date: 2025-05-28)

• Primary citation: Abu-Shmais, A.A.,Guo, L.Q.,Miller, R.J.,Janke, J.K.,Vukovich, M.J.,Lindsay, E.B.,Rush, S.A.,Wolter, R.M.,Kose, N.,Carnahan, R.H.,Crowe, J.E.,Bonami, R.H.,Mousa, J.J.,McLellan, J.S.,Georgiev, I.S.; Potent cross-neutralizing RSV/hMPV antibody targeting antigenic site V; To Be Published,

Experimental method

ELECTRON MICROSCOPY (4.24 Å)