9CAF

Cryo-EM structure of the reconstituted TRRAP lobe of the human TIP60 complex (composite structure)

Summary for 9CAF

• Entry DOI: 10.2210/pdb9caf/pdb
• EMDB information: 45389
• Descriptor: E1A-binding protein p400,Haloalkane dehalogenase chimera, Isoform 2 of Transformation/transcription domain-associated protein, INOSITOL HEXAKISPHOSPHATE (3 entities in total)
• Functional Keywords: histone acetyltransferase, chromatin regulator, transcription regulation, gene regulation
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 559675.04

Authors

Louder, R.K.,Park, G.,Patel, A.B. (deposition date: 2024-06-17, release date: 2025-06-18)

• Primary citation: Park, G.,Patel, A.B.,Wu, C.,Louder, R.K.; Structural divergence of H2A.Z-associated human chromatin remodelers SRCAP and TIP60; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.35 Å)