9BP8

Crystal structure of BRAF kinase domain with PF-07799933

This is a non-PDB format compatible entry.

Summary for 9BP8

• Entry DOI: 10.2210/pdb9bp8/pdb
• Descriptor: Serine/threonine-protein kinase B-raf, N-{(1R,2P)-6-chloro-5-[(5-chloro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]-4-fluorocyclohexa-2,3,5-trien-1-yl}-3-fluoroazetidine-1-sulfonamide, DIMETHYL SULFOXIDE, ... (5 entities in total)
• Functional Keywords: braf, encorafenib, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 34099.26

Authors

Mou, T.-C. (deposition date: 2024-05-07, release date: 2025-05-14)

• Primary citation: Mou, T.-C.; Crystal structure of BRAF kinase domain with PF-07799933; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.73 Å)