9BDW

NF-kappaB RelA homo-dimer bound to GC-centric kappaB DNA

Summary for 9BDW

• Entry DOI: 10.2210/pdb9bdw/pdb
• Descriptor: Transcription factor p65, DNA (5'-D(P*AP*CP*TP*GP*GP*GP*AP*AP*GP*TP*TP*CP*CP*AP*GP*TP*GP*AP*T)-3'), DNA (5'-D(P*AP*TP*CP*AP*CP*TP*GP*GP*AP*AP*CP*TP*TP*CP*CP*CP*AP*GP*T)-3'), ... (6 entities in total)
• Functional Keywords: rela, kappab dna, promoter, transcription, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 4
• Total formula weight: 78160.70

Authors

Biswas, T.,Shahabi, S.,Tsodikov, O.V.,Huang, D.,Ghosh, G. (deposition date: 2024-04-12, release date: 2024-04-24, Last modification date: 2024-06-12)

• Primary citation: Li, T.,Shahabi, S.,Biswas, T.,Tsodikov, O.V.,Pan, W.,Huang, D.B.,Wang, V.Y.,Wang, Y.,Ghosh, G.; Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA.; Proc.Natl.Acad.Sci.USA, 121:e2405555121-e2405555121, 2024; PubMed: 38805268; DOI: 10.1073/pnas.2405555121

Experimental method

X-RAY DIFFRACTION (1.87 Å)