9B91
Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium and ATP at 37 degrees Celsius
Summary for 9B91
Entry DOI | 10.2210/pdb9b91/pdb |
EMDB information | 44365 |
Descriptor | Transient receptor potential cation channel subfamily M member 4, CALCIUM ION, ADENOSINE-5'-TRIPHOSPHATE (3 entities in total) |
Functional Keywords | ion channel, trp channel, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 135043.82 |
Authors | |
Primary citation | Hu, J.,Park, S.J.,Walter, T.,Orozco, I.J.,O'Dea, G.,Ye, X.,Du, J.,Lu, W. Physiological temperature drives TRPM4 ligand recognition and gating. Nature, 630:509-515, 2024 Cited by PubMed: 38750366DOI: 10.1038/s41586-024-07436-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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