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9B91

Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium and ATP at 37 degrees Celsius

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Transient receptor potential cation channel subfamily M member 4polymer1214134456.51UniProt (Q8TD43)
Pfam (PF18139)
Pfam (PF00520)
Homo sapiens (human)hTRPM4,Calcium-activated non-selective cation channel 1,Long transient receptor potential channel 4,LTrpC4,Melastatin-4
2B, C
(A)
CALCIUM IONnon-polymer40.12Chemie (CA)
3D
(A)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (ATP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight134456.5
Non-Polymers*Number of molecules3
Total formula weight587.3
All*Total formula weight135043.8
*Water molecules are not included.

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PDB entries from 2025-07-09

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